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Discovery Laboratories, Inc. (NASDAQ: DSCO), a specialty biotechnology company dedicated to advancing a new standard in respiratory critical care, today announced the release of two peer-reviewed publications related to AFECTAIR(R) , the Company's proprietary aerosol-conducting airway connector designed with the goal of simplifying and improving aerosolized medication delivery to infants requiring mechanical ventilation in the neonatal and pediatric intensive care units.

"Discovery Labs has had a long-standing commitment to presenting our scientific findings through the peer review process,For mains, there is a choice of Wild Rice’s ‘Chinese Fish ‘n Chips’ (beer-battered ling cod, Asian Tartar Sauce, taro shoestring frites) or its ‘meaty’ Grilled king oyster mushroom (with cashew ricotta and polenta fries). thereby providing the scientific rigor and transparency expected by healthcare professionals today," said Dr. Russell G.Our full range of portable ultrasonic Flaw Detector (UT) provides unmatched capabilities for locating discontinuities and other flaws. Clayton, Senior Vice President, Research & Development, of Discovery Labs. "Our goal is to better inform healthcare professionals about our products and the patients who might benefit from our novel technologies.The approach uses fine Titanium Wire, laid one on another like a potter working with coils of clay. These wires are then smelted together in the rough shape of the desired component, cutting wasted material from potentially as much as 70 percent to as little as 10 percent."

The two publications are as follows:

Aerosolized albuterol sulfate delivery under neonatal ventilatory conditions -- in vitro evaluation of a novel ventilator circuit patient interface connector - Journal of Aerosol Medicine and Pulmonary Delivery.

The goal of this in vitro study, previously presented at the 2012 Hot Topics in Neonatology Annual Meeting,profile projector is a shop tool used by designers and quality control technicians to view the profile of small machined parts as magnified image on screen. was to characterize the delivery of aerosolized albuterol sulfate, a medication commonly delivered in aerosolized form, under simulated neonatal ventilatory conditions using AFECTAIR. Authors of the study found that use of AFECTAIR resulted in an increased delivery of albuterol sulfate at the patient interface compared with the method currently used to introduce aerosolized medication into the ventilator circuit. In addition, the aerosol characteristics at the patient interface were more consistent with the aerosol characteristics produced by the nebulizer when the aerosolized medication was delivered through AFECTAIR compared with the currently used method. Authors concluded that AFECTAIR may be a useful, new approach for the delivery of aerosolized medications to neonates requiring positive pressure ventilatory support.

Safety Assessment of a Novel Neonatal Ventilator Circuit Patient Interface Connector for the Delivery of Aerosolized Medication to Mechanically Ventilated Infants -- Respiratory Therapy. February-March 2013, Vol. 8, No. 1, Pages 29-33

As part of a safety assessment of AFECTAIR, studies were conducted to determine the dead space volume (volume of gas that remains in device, undelivered to the patient), the resistance to gas flows through AFECTAIR relative to a standard configuration, as well as the interaction between the ventilator circuit gas and the aerosol carrier gas using the two configurations. Authors concluded that, when used correctly,The Spectrophotometer is an instrument which measures the amount of light of a specificed wavelength which passes through a medium. AFECTAIR has a comparable safety profile to standard wye connectors and aerosol delivery configurations. Authors also stated that further studies are needed to determine the impact of AFECTAIR on the delivery of aerosolized medications to mechanically ventilated infants.

Use of AFECTAIR may result in an increase in the delivery of aerosolized medication to patients receiving mechanical ventilation.Highly capable, 3-axis non-contact video measuring machine, suitable for both simple shop-floor quality control and advanced manufacturing inspection applications ... When delivering aerosolized medication through AFECTAIR to patients receiving mechanical ventilation, a qualified healthcare personnel should closely monitor the response to the aerosolized medication.